Mechanism for the Reduced Dissolution of Ritonavir Tablets by Sodium Lauryl Sulfate
نویسندگان
چکیده
منابع مشابه
Final Report on the Safety Assessment of Sodium Lauryl Sulfate and Ammonium Lauryl Sulfate
Sodium and Ammonium Lauryl Sulfate are anionic surfactants used in cosmetics as cleansing agents. In absorption, metabolism, and excretion studies, Sodium Lauryl Sulfate had a degenerative effect on the cell membranes because of its protein denaturing properties. Low levels of skin penetration may occur at high use concentration. Sodium Lauryl Sulfate had an LD50 of 0.8 to 1.10 g/kg in rats. A ...
متن کاملInfluence of Sodium Lauryl Sulfate and Tween 80 on Carbamazepine–Nicotinamide Cocrystal Solubility and Dissolution Behaviour
The influence of the surfactants of sodium lauryl sulfate (SLS) and Tween 80 on carbamazepine-nicotinamide (CBZ-NIC) cocrystal solubility and dissolution behaviour has been studied in this work. The solubility of the CBZ-NIC cocrystal was determined by measuring the eutectic concentrations of the drug and the coformer. Evolution of the intrinsic dissolution rate (IDR) of the CBZ-NIC cocrystal w...
متن کاملstudy of cohesive devices in the textbook of english for the students of apsychology by rastegarpour
this study investigates the cohesive devices used in the textbook of english for the students of psychology. the research questions and hypotheses in the present study are based on what frequency and distribution of grammatical and lexical cohesive devices are. then, to answer the questions all grammatical and lexical cohesive devices in reading comprehension passages from 6 units of 21units th...
Effect of Binders on the Dissolution Rate and Dissolution Efficiency of Ritonavir Tablets
Ritonavir, a widely prescribed anti-retroviral drug, belongs to Class II under 'BCS' and exhibit low and variable oral bioavailability due to its poor aqueous solubility. Ritonavir is practically insoluble in water and aqueous fluids. Its aqueous solubility was reported to be 2.56 mg/100 ml. As such oral absorption of ritonavir is dissolution rate limited and it requires enhancement in solubili...
متن کاملSodium lauryl sulfate and recurrent aphthous ulcers. A preliminary study.
Sodium lauryl sulfate (SLS), a synthetic detergent commonly used in dentifrices, is an effective denaturant. The aim of the present study was to investigate the effect of SLS in patients with recurrent aphthous ulcers (RAU). Ten patients with multiple minor RAU participated in the study. The mean incidence of RAU was 17.8 during a 3-month period before the study. The patients used a dentifrice ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Pharmaceutical Sciences
سال: 2019
ISSN: 0022-3549
DOI: 10.1016/j.xphs.2018.10.047